However, scant data focused on its protective impact on gastrointestinal system and whether green tea using as a flavor could reduce side effects during bowel preparation remains unknown. Few studies investigated its inhibition of bacterial infection. Recently, more studies showed its potential benefits in the fields of anti-cancer effects, protection of cardiovascular system and improvement of neurological and spiritual disorders. Green tea has played a significant role in the Chinese traditional culture and lives. This results in poor tolerance from patients which lead to incomplete administration of the polyethylene glycol electrolyte solution and in turn influence the efficacy of bowel preparation. However, during the process of ingestion of PEG solution, the majority of the patients develop adverse reactions, such as nausea, vomiting, abdominal distention and pain, due to its bitter taste. At present, polyethylene glycol electrolyte powder has become the most common bowel cleanser during the process of bowel preparation. Based on the investigation and the comparison of a large number of clinical studies, the ‘consensus of bowel preparation in colonoscopy’ published by the American Society of Gastrointestinal Endoscopy (ASGE), the American Society of Colon and Rectal surgeons (ASCRS) and the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) in 2006, suggested that polyethylene glycol electrolyte solution (PEG) is a fast and effective method for bowel cleansing with improved tolerance, which is considered superior to the high-dose laxatives and mannitol that require patient fasting. Currently, the bowel preparation prior to colonoscopy has been developed recently from earliest diet preparation and subsequent enema using to oral medication currently. Incomplete preparation of the bowel can directly lead to insufficient exposure of colonic mucosa and may result in incorrect or missed diagnosis of bowel lesions. This trial was retrospectively registered on Feb 1st, 2019 ( ChiCTR1900021178).Īdequate bowel preparation is an important factor that ensures the smooth implementation of colonoscopy. ConclusionsĬoncomitant use of green tea and polyethylene glycol may effectively reduce incidence of adverse events, increase compliances, with comparable bowel cleanliness in bowel preparation. Patients in group PEG+GT who have probabilities to receive repeating colonoscopy had a higher willingness to accept PEG+GT again for bowel preparation, compared with PEG group (94.9% vs 57.9%, p < 0.001). Rates of adverse events as nausea and vomiting, abdominal pain in bowel preparation were significantly different between two groups (55.9% vs 77.2%, p = 0.015 and 13.6% vs 33.3%, p = 0.012). ![]() Mean Aronchick scale between two groups were 2.0 ± 0.9 versus 2.2 ± 0.7 respectively (PEG+GT vs PEG, p = 0.296). Full compliances were achieved in 93.2% patients of group PEG+GT and 59.6% of group PEG ( p < 0.001). ResultsĪ total of 116 patients were enrolled in this study (PEG+GT 59, PEG 57). The bowel cleanliness of each patient was evaluated according to the Aronchick indicators. ![]() ![]() ![]() Admitted doses of PEG solutions, taste evaluation, adverse reactions (nausea and vomiting, distention and abdominal pain) were investigated by questionnaires. Patients aged 18 through 80 who were scheduled to undergo colonoscopy between August 2015 and February 2016 were randomly assigned into two groups, admitting either 2 L-PEG solutions with 1 L GT liquids or 2 L-PEG solutions only for bowel preparation. It was conducted at an outpatient setting of colorectal surgery in a tertiary hospital. This was a prospective, randomized controlled study. This study aimed to evaluate the effectiveness and safety of concomitant use of green tea (GT) with PEG in bowel preparation prior to colonoscopy. However, patients often exhibited adverse events as nausea, vomit and distention due to its uncomfortable tastes and potential side affects. Polyethylene glycol solution (PEG) is widely used for bowel preparation prior to colonoscopies.
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